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Challenges and Controversies in Choosing a Model Organism

Image Credit: (L to R) Michelle Tribe; André Karwath; Paul Asman and Jill Lenoble Selection of an appropriate model organism is a vital step in good experimental design. A number of articles published...

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Exploring the Possibility of HIV Treatment as Prevention: Interview with...

Image credit: Psyberartist at flickr.com, Manta Ray Media/HIV Modelling Consortium To mark the launch of the PLoS Medicine collection “Investigating the Impact of Treatment on New HIV Infections”, I...

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Getting a gender agenda into HIV/AIDS research

Why aren’t sex and gender issues higher up the agenda in HIV/AIDS research? That was the topic of a panel discussion I participated in on Monday 23rd July at the biannual International AIDS Conference,...

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Do No Harm: How a US-Led Free Trade Agreement Threatens the Prospects for an...

The theme of the 19th International AIDS Conference that took place in Washington, DC a few days ago was ‘Turning the Tide Together.’ It captured the inspiring optimism and momentum around HIV/AIDS....

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Why the United States Needs Better Confidentiality Laws for Minors with HIV/AIDS

At the beginning of the International AIDS Conference held in Washington, D.C. in July, Secretary of State Hillary Clinton renewed the United States’ commitment to an “AIDS-free generation a call to...

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Cryptococcal Meningitis: A Major Killer in HIV/AIDS Programmes in...

Daniel O’Brien reflects on the challenges of treating cryptococcal meningitis in developing countries. Being a doctor in the era of bringing antiretroviral treatment (ART) to HIV-infected populations...

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Addressing TB in the Mines: Complementing Political Will with an Urgent Need...

Guest blogger Jonathan Smith from Yale University School of Public Health discusses the challenges of tackling South Africa’s “TB factories.” TB in the South African mining industry has recently seen...

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Gathering the Evidence to Improve Health Care in Developing Countries:...

Nathan Ford and Philipp du Cros  from Médecins Sans Frontières ask whether it is time for ‘Meta-analysers without Borders’ A couple of sample dilemmas faced recently in the clinical programmes of the...

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Xpert MTB/RIF for those with HIV; the importance of considering equity

Anna Vassall from the London School of Hygiene and Tropical Medicine discusses a recently published analysis of the potential health and economic consequences of implementing Xpert MTB/RIF in southern...

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What can we learn from disease stigma’s long history?

Sara Gorman from Harvard University takes a look at the history of infectious disease stigma. Although tremendous strides in fighting stigma and discrimination against people with HIV/AIDS have been...

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Giving back to research participants

“You have been asking me questions and taking my blood for years but I do not know anything about what you have found.” Yesterday we published an article by David Bangsberg and colleagues that...

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Familiar Enemies in Conflict and TB

Charles Ssonko from Médecins Sans Frontières reflects on the challenges of treating TB in unstable settings. Amid the justified excitement surrounding the development of the first new drugs to treat TB...

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This Week in PLOS Medicine: ART in South Africa, Herpes Zoster Vaccine, & PRISMA

Image Credit: Flikr Horia Varlan PLOS Medicine published three articles this week, spanning research topics from life expectancy on ART in South Africa to the shingles vaccine for US seniors. Leigh...

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Why Should We Care About Measuring Coverage of Maternal, Newborn, and Child...

Jennifer Bryce explains why measuring coverage of maternal, newborn, and child health interventions matters and what we can learn from the new PLOS Collection Coverage matters! Coverage matters,...

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Why Measure Coverage?

Dr. Lucy Chappell, Collection Editor of Measuring Coverage of Maternal, Newborn, and Child Health, explains what researchers of MNCH in High Income Country settings can learn from the Collection. In...

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This Week in PLOS Medicine: CD4 Count vs Viral Load for HIV Monitoring, LMIC...

This week PLOS Medicine publishes the following new articles: Image Credit: NIAID, Flickr Marc Lallemant and colleagues report that, for adults infected with HIV in Thailand, a monitoring strategy...

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This Week in PLOS Medicine: Dementia Guidelines, COIs & Disease Definitions,...

This week PLOS Medicine publishes the following new articles: Image Credit: Dierk Schaefer, Flickr Ethical issues are important for clinical practice guidelines (CPG) to address, for the medical...

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This Week in PLOS Medicine: Reporting Guidelines Collection, Dementia &...

This week PLOS Medicine publishes the following new articles: Image Credit: CCAC North Library, Flickr The PLOS Medicine Editors announce a new Reporting Guidelines Collection— an open access...

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HIV Viral Load Testing in Africa – No Longer Why but How?

Helen Bygrave from Médecins Sans Frontières (MSF) considers the challenges of making HIV viral load testing an effective reality in sub-Saharan Africa Access to viral load monitoring for patients...

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Advances in HIV Mucosal Immunology: Challenges and Opportunities

Florian Hladik from the University of Washington and the Fred Hutchinson Cancer Research Center in Seattle, USA, explains why recent research on how to study the rectal and genital mucosa – featured in...

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